Small Fiber Neuropathy: A Clinical and Practical Approach

Small fiber neuropathy: a common and important clinical disorder.

Small fiber neuropathy (SFN) is a neuropathy selectively involving small diameter myelinated and unmyelinated nerve fibers. Interest in this disorder has considerably increased during the past few years. It is often idiopathic and typically presents with peripheral pain and/or symptoms of autonomic dysfunction. Diagnosis is made on the basis of the clinical features, normal nerve conduction stu...

Small fiber neuropathy: A burning problem.

Small fiber neuropathy is increasingly being recognized as a major cause of painful burning sensations in the feet, especially in the elderly. Although strength remains preserved throughout the course of the disease, the pain and paresthesias are often disabling. Diabetes mellitus is the most common identifiable cause of small fiber neuropathy, and impaired oral glucose tolerance and individual...

Practical Approach to Peripheral Neuropathy

Peripheral neuropathy occurs as a component of several common and many rare diseases. It is heterogeneous in etiology, diverse in pathology, and varied in severity. Peripheral neuropathy is often overlooked, underestimated and not evaluated in day to day practice. The prevalence of neuropathy is well studied in patients with diabetes mellitus in most of the studies and other causes of neuropath...

The clinical approach to small fibre neuropathy and painful channelopathy

Small fibre neuropathy (SFN) is characterised by structural injury selectively affecting small diameter sensory and/or autonomic axons. The clinical presentation is dominated by pain. SFN complicates a number of common diseases such as diabetes mellitus and is likely to be increasingly encountered. The diagnosis of SFN is demanding as clinical features can be vague and nerve conduction studies ...

Chapter 7 Small fiber neuropathy in sarcoidosis